Radmacher Group


Research

The research in the Radmacher lab focuses on the investigation of biological and biophysical processes. Examples are cell dynamics, cell mechanics, cell migration, cell division, activity of single enzyme molecules and enzymatic nanolithography. The most important tool for these investigations is the atomic force microscope (AFM). The AFM allows to investigate biological samples without any chemical fixation under physiological conditions combined with a high accuracy in positioning a very small tip and a high sensitivity in measuring and applying forces. This combination allows for instance to investigate biological processes from a cellular level down to single molecules. Although the AFM has been invented as an imaging device it has found recently several applications, where it is used for either to measure or to apply locally small forces on a sample. To learn more on AFM please click here.

Group Members

Click here to view our group members.

Publications

Some of the latest publications in refereed Journals

 

To view more please click here.

 

C. Rianna, M. Radmacher.

Comparison of viscoelastic properties of cancer and normal thyroid cells on different stiffness substrates.

M. Eur Biophys J (2016).

 

K. Apte, R. Stick, M. Radmacher.

Mechanics in human fibroblasts and progeria: Lamin A mutation E145K results in stiffening of nuclei.

J Mol Recognit. (2016).

 

A. Yango, J. Schäpe, C. Rianna, H. Doschke, M. Radmacher.

Measuring the viscoelastic creep of soft samples by step response AFM.

Soft Matter (2016) 12, 8297-830.

Image Gallery

 To view more please click here.

Movies

We have prepared several animations of different topics.

To view more click here.

Data Analysis

Here you can get a specific overview of our method how to analyse data.